The Mausoleum at Halicarnassus

The Mausoleum at Halicarnassus was a large and ornate mausoleum built both to honor and hold the remains of Mausolus of Caria. When Mausolus died in 353 BCE, his wife Artemisia ordered the construction of this vast structure in their capital city, Halicarnassus (now called Bodrum) in modern Turkey.  Ã‚  Ultimately, both Mausolus and Artemisia were buried inside. The Mausoleum, considered one of the Seven  Ancient Wonders of the World,  retained its grandeur for nearly 1,800 years until earthquakes in the 15th century destroyed part of the structure. Eventually, nearly all of the stone was taken away  to be used in nearby building projects,  particularly for  a Crusader castle. Mausolus Upon the death of his father in 377 BCE, Mausolus  became the satrap (a  regional governor  in the Persian Empire)  for Caria. Although only a satrap, Mausolus was like a  king in his realm,  ruling for 24 years. Mausolus was descended from the indigenous herdsmen of the area, called Carians, but appreciated Greek culture and society. Thus, Mausolus encouraged  the Carians to  leave  their lives as  herdsmen and embrace the Greek way of life. Mausolus was also  all about expansion. He moved his capital city from Mylasa to the coastal city of Halicarnassus and then worked on a  number of projects to  beautify the city, including building a large palace for himself. Mausolus  was also politically savvy and was thus able to add several nearby cities to his  realm. When Mausolus died in 353 BCE, his wife Artemisia, who also happened to be his sister, was grief-stricken. She wanted the most beautiful tomb built for her departed husband. Sparing no expense, she hired the very best sculptors and architects  that money could buy. It is unfortunate that Artemisia died just two years after her husband, in 351 BCE, not seeing the Mausoleum of Halicarnassus completed. Mausoleum of Halicarnassus Built from  about 353 to 350 BCE, there were five famous sculptors that worked on the exquisite tomb. Each sculptor had a portion that they were responsible for --  Bryaxis (north side), Scopas (east side), Timotheus (south side), and Leochares (west side). The chariot on top was  created by Pythias. The structure of the Mausoleum was made up of three parts: a  square base on the bottom, 36 columns (9 on each side) in the middle, and then topped by a stepped pyramid that had 24 steps. All of this was covered in ornate carvings, with life-size and larger-than-life statues abounding. At the very top was the piece de resistance; the chariot. This 25-foot-high marble sculpture consisted of standing  statues of both Mausolus and Artemisia riding in a chariot pulled by four horses. Much of the Mausoleum was made out of marble and the entire structure reached 140 feet high. Although large, the Mausoleum of Halicarnassus was known more for its ornate sculptures and carvings. Most of these were painted in vibrant colors. There were also friezes that wrapped around the entire building. These were extremely detailed and included scenes of battle and hunting, as well as scenes  from Greek mythology that included such mythic animals as centaurs. The Collapse After 1,800 years,  the long-lasting Mausoleum was destroyed by earthquakes that occurred  during the 15th century CE in the region.  During and after that time,  much of the marble was carried away in order to build other buildings, most especially a Crusader fortress held by the Knights of St. John.  Some of the elaborate sculptures were moved into the fortress as decoration. In 1522 CE, the crypt that for so long had safely held the remains of Mausolus and Artemisia was raided. Over time, people forgot exactly where the Mausoleum of Halicarnassus had stood. Houses were built on top. In the 1850s, British archaeologist Charles Newton recognized that some of the decorations at Bodrum Castle, as the Crusader fortress was now called, could have been from the famous Mausoleum. After studying the area and excavating, Newton found the  site of the Mausoleum.  Today, the British Museum in London contains statues and relief slabs from the Mausoleum of Halicarnassus.  Ã‚   Mausoleums Today Interestingly, the modern word mausoleum, which means a building used as a tomb, comes from the name Mausolus, for whom this wonder of the world was named. The tradition of creating mausoleums in cemeteries continues around the world today.  Families and individuals build mausoleums, both large and small,  in their own or others honor following their deaths.  In addition to these more  common mausoleums,  there are other, larger mausoleums that are tourist attractions today.  The worlds most famous mausoleum is the Taj Mahal in India.

Trifles by Susan Glaspell Essay - 925 Words

Sister Love The play entitled â€Å"Trifles,† by Susan Glaspell, begins as a murder mystery that turns into a drama as the story unfolds. The story is focused on the investigation of a murder that took place in a farm house. The investigators, who are all men, are in the farm house looking for forensic evidence to help them solve the murder. The wives of two of the investigators are there to retrieve personal items for the wife of the victim. Mrs. Wright, who is the wife of the victim, is in jail as the primary suspect of her husband’s murder. When the story begins, all the characters are in the kitchen engaging in small talk. One of the investigators is criticizing the state of the kitchen by complaining that it is dirty and†¦show more content†¦The behavior of men towards women in a patriarchal society is described by Manju when she describes society in India by stating, â€Å"In Indian society stress is given to create female persona for different stages, docile daughters, chase and obedient wives and sacrificing mothers. The only domain ascribed to female is to fit in this good daughter, good wife and good mother criteria. Husband and wife are considered soul mates. But man assumes himself superior to woman, and he never tries to create emotional bonding with his wife, to understand her wishes or act according to her consent† (234). The rest of this paper will analyze the effects that male dominance had on the women. Throughout the story, the constant criticism of the women’s behavior by the men caused the female characters to develop a kinship and bond; they form a sisterhood. In one of the scenes, the attorney is angry that the towels in the kitchen are dirty. He kicks some pans that are under the sink and accuses Mrs. Wright (the victim’s wife) of not being a good house keeper. Mrs. Hale, one of the women, reminds the attorney that towels get dirty because men’s hands aren’t always clean. At first we suspect that the two women are friends but when the attorney asks her if they were friends Mrs. Hale responds by saying â€Å"I’ve not seen much of her of late years. I’ve not been in this house—it’s more than a year.† After the men leave, Mrs. Hale reorganizes the pans thatShow MoreRelatedTrifles, By Susan Glaspell Essay2136 Words   |  9 Pagesprimarily of a domestic nature. Trifles by Susan Glaspell indicates that a man†™s perspective is entirely different from a woman’s. The one-act play, Trifles, is a murder mystery which examines the lives of rural, middle-aged, married, women characters through gender relationships, power between the sexes, and the nature of truth. The play, written in the early 1900s, long before the women’s movement and while men considered women their possessions. In the story of Trifles, it is easy to recognize theRead MoreTrifles by Susan Glaspell1158 Words   |  5 PagesAnalytical Essay on Drama Trifles by Susan Glaspell Heidi Barnard South University Trifles’ By Susan Glaspell I believe had several small defining moments leading to the one larger defining moment, which brings together all of them together. The defining moment is the discovery of the dead bird hidden in the pretty red box, this leads back to smaller points such as her sewing and the bird cage. â€Å" Here’s some red. I expect this has got sewing things in it. (Brings out a fancy box.) What aRead MoreTrifles By Susan Glaspell1000 Words   |  4 Pages  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚     In Trifles by Susan Glaspell, the author presents a predominant  theme of women and femininity. This theme reflects upon the underlying message of the play, that women are not treated fairly and are not seen in the same light as men. Susan Glaspell demonstrates the common assumptions made by men towards women in terms of roles and degrading their value/insight. Throughout the play, Glaspell provides many instances to where a woman’s value or insight is degraded. Hale demonstrates thisRead MoreTrifles by Susan Glaspell604 Words   |  2 Pages Trifles by Susan Glaspell is a one-act play that explores the theme of the gender roles and social positions of men and women in early twentieth-century America. The play is loosely based on the true event of the murder of John Hossack which Glaspell reported on while working as a news journalist in Iowa. Years later, she used her experiences and observations to create the play. Trifles is about solving the murder case of farmer John Wright. While Mr. Wright was asleep in the night, someoneRead MoreTrifles, By Susan Glaspell1034 Words   |  5 Pagessay goes. The 1912 play Trifles, by Susan Glaspell, who was inspired to write this play from a story she covered as a reporter. A murder case is being held and authorities are getting down to it suspecting a woman of killing her husband in his sl eep. The character Mrs. Hale who is neighbors and friends with Mrs. Peters, the sheriff’s wife and Mrs. Wright, the woman accused of the murder of her Husband, Mr. Wright. The character Mrs. Hale, in the Susan Glaspell s play Trifles, is displayed as a empoweringRead MoreTrifles, By Susan Glaspell Essay1469 Words   |  6 PagesSusan Glaspell’s one-act play Trifles is based on the murder investigation of John Wright. Minnie Wright’s isolation and the death of her canary are the major factors that led to the murder of her husband. Glaspell stresses the perceived supremacy of males when investigating the murder by giving the men lead roles in the investigation and by making fun of the â€Å"trifles† that the women are choosing to observe. It is ironic because the ordinary items observed by the women were thought of as â€Å"trifles†Read MoreTrifles : Susan Glaspell s Trifles940 Words   |  4 PagesWhat is a trifle? A trifle is something that ha s little to no importance (dictionary.com). For instance, the color of your nails would be considered a trifle. In Trifles by Susan Glaspell, women are criticized and made fun of by men because of the little things they worry about, such as the color of their nails or their hair. This exhibits the gender role difference portrayed during the play’s time period. The central conflict is what the plot is centered around. In Trifles, the central conflictRead MoreSusan Glaspell s Trifles 1507 Words   |  7 Pagesâ€Å"Trifles† is a one act play written by Susan Glaspell in 1916, which was first performed on August 8th by the Provincetown Players in Provincetown, Massachusetts at the Wharf Theater. The author, Susan Glaspell, was born on July 1, 1876 in Davenport, Iowa. Over her lifetime she had become proficient in many different professions: Playwright, Actress, Novelist, and Journalist. For her works, she won an American Pulitzer Prize in 1931. The Provincetown Players was founded by Susan Glaspell and herRead MoreSusan Glaspell s Trifles 1732 Words   |  7 PagesSusan Glaspell (1876-1948) was an American-born Pulitzer Prize winning writer of both plays and fiction. Glaspell came from humble beginnings and went on to study at Drake University and the University of Chicago. Much of Glaspell s work dealt with the relationships between men and women and the negative effects they have on women. In Glaspell s play Trifles, it is revealed that the operations of patriarchy are just an illusion that men have created to make themselves feel superior to womenRead MoreTrifles by Susan Glaspell Essay1253 Words   |  6 Pages Susan Glaspell’s most memorable one-act play, Trifles (1916) was based on murder trial case that happened in the 1900’s. Glaspell worked as a reporter, where she appointed a report of a murder case. It was about a farmer, John Hossack who was killed while he was asleep in bed one night. His wife claimed that she was asleep next to him when the attack occurred. No one believed in her statement, she was arrested and was charged on first degree murder. In Trifles, the play takes place at an abandon

We Can Raise Antibodies Against a Specific Antigen, How Free Essays

We Can Raise Antibodies Against a Specific Antigen, How? BY loveyal 2345 Midterm 2 Review Antibodies Experimental Purpose: We can â€Å"raise† antibodies against a specific antigen (protein of interest) How? Polyclonal: 1 antigen with many antibodies that bind to specific sites on the antigen (Received by injecting animal with protein of interest, waiting for that animal to build antibodies (B-lymphocytes). The lymphocytes are then extracted which give us the polyclonal antibodies. Monoclonal: I antibody that binds to a specific site on the antigen. We will write a custom essay sample on We Can Raise Antibodies Against a Specific Antigen, How or any similar topic only for you Order Now (These are received by the same way as polyclonal, expect you only extract ne antibody, and place that into a cancer cell to create a chimera of the two, the immortal cancer cell then acts like the monoclonal antibody. ) These are the best to use in experiments because they are specific to only ONE protein of interest. These antibodies can used in experiments to: Purify a protein of interest Visualize a particular protein in a live system or in a gel How Probe the gel to visualize where a protein is. Probing Protein Structure 1) X-ray crystallography – Spend h your life producing sufficiently pure protein and obtaining a crystal protein (Crystallizing the proteins is a hard process) â€Å"Shoot† crystal protein with light, electrons, or radiation and examine the diffraction patterns with extremely powerful computers -Analyze all the data while considering the amino-acid sequence and build a 3-D model of the protein. ) NMR-Nuclear Magnetic Resonance (Used rarely) – For small proteins only – â€Å"Shoot† concentrated pure proteins with strong magnetic field to generate hydrogen atom vibrations. – Use computer program to measure reconstruct the structure of the protein by measuring the hydrogen atom vibrations. Mass spectrometry is used as a precursor to both of these experiments. It generates the amino-acid sequence. Protein Purification 1) Grow Cells with protein of interest (transferred on plasmid or native cell) 2) Lyse Cells -homogenization of tissues†did in lab -cell lysis buffers†break cell membrane -sonication†send sound waves through the cell to break membrane -pin-hole lysis†push mixture through an extremely tiny hole (Force large molecules through a small opening causes them to break apart) 3) Centrifugation A) Regular Centrifugation B) Differential Centrifugation: Sequential centrifugation @ increasing speeds (lowohigh) -low speed pellets = big things -high speed pellets= small things C) Velocity Centrifugation layer cell and lysate over a â€Å"density gradient† and centrifuge to separate by density. Remove layers to separate proteins. D) Equilibrium Sedimentation: another name for C 4) Column Cromatography 3 types Ion exchange (charge separation)†protein adheres to beads of an opposite charge Gel filtration (size separation)†matrix has holes, the large proteins come out last Affinity (Affinity separation)†beads have something on it that only your protein binds to. ) Electrophoresis (small volume separation or detection) -use polyacrylimide gel (creates a â€Å"mesh† in the gel to separate proteins by size and charge. separates denatured proteins 6) Isoelectric focusing based on isolelectric point of protein†2D electrophoresis Griffiths Experiment Conclusion: heat killed bacteria transformed nonviolent bacteria Extract of heat killing S-strain transform R-strain to become S-strain Isolated â€Å"transforming material† (TM) and determined it was DNA not proteins that carried genetic information. (Took 1 5 years) How do we test Added proteases Injected into mouse Mouse should live ( According to beliefs during that time period) Mouse however dies Added nucleases Mouse should die (According to beliefs during that time period) Mouse however lives This illustrated that DNA carried the genetic information Hershey-chase Experiments Bacteriophages†virus that infect bacteria Inject DNA into bacteria (naked)†DNA unprotected by proteins Protein shell left outside of bacteria Label phages Label protein 7 groups of phages Label DNA in other groups of phages Mix both phage types with bacteria Blend bacterial mixture so that any viral parts outside the cell are ripped off Pellet bacteria and observe that only DNA label types is seen in pelleted bacteria Proved DNA carries genetic information 1) Grow bacteria with light DNA (14N) and heavy DNA (1 5N) which will separate to ifferent levels upon density-gradient centrifugation 2) Transfer heavy DNA and place in flask with light isotope Allows to eliminate conservative view 3) Heat DNA from step 2 to make it single stranded, then centrifuge. How to cite We Can Raise Antibodies Against a Specific Antigen, How, Papers